Antibacterial and phytochemical constituent of Etlingera rubroloba A.D. Poulsen extract, an endemic ginger from Wallacea Region, Indonesia

Abstract. Andila PS, Nugroho LH. 2022. Antibacterial and phytochemical constituent of Etlingera rubroloba A.D. Poulsen extract, an endemic ginger from Wallacea Region, Indonesia. Biodiversitas 23: 3646-3658. (Blume) AD is one the wild species Zingiberaceae which a native in region has not been studied well for its biology potential. This study aimed to investigate potential antibacterial activity hexane extract leaves rhizome E. their content. The test was carried out by agar disc diffusion method against several human pathogenic bacteria be measured Minimum Inhibitory Concentration (MIC) Zone inhibition. profile tested total phenol content (TPC), flavonoid (TFC) GC-MS analysis. results show that TPC extracts respectively 15.68±0.80 mg Gallic Acid Equivalent (GAE)/g sample (leaves) 11.89±0.76 GAE/g (rhizomes), while TFC value were 33.99±2.24 Quercetin (QE)/g 32.46±0.67 QE/g (rhizomes). revealed effective Bacillus cereus ATCC11778 (with MIC 0.5 mg/mL using 1 rhizomes), but it Escherichia coli ATCC 25922, Staphylococcus aureus 25923 epidermidis ATCC12228. contained 28 58 compounds identified leaf rhizome, respectively. dominant (Pentadecanoic acid, 14-methyl-, methyl ester; Methyl stearate) (Hexadecanoic ethyl Isopropyl myristate; 9-Octadecenoic acid (Z)-, 9,12- Octadecadienoic ester, (E,E)-) known have activity. Based on studies, can suggested as agent.